带状疱疹是癌前预警吗?
不是,这不叫癌前预警。
只能说带状疱疹和患癌有一定相关性,有文献显示,患有带状疱疹的人得癌的风险是普通人的2.42倍,但不叫癌前预警。
如果这也叫癌前预警,那喝酒、吸烟、肥胖都意味着癌症风险增高,尤其是吸烟,重度吸烟患肺癌风险是20倍以上,岂不是天天预警。
最多只能说带状疱疹和患癌轻度相关,文献如附图所示。
结论很清楚,如下,带状疱疹患者的风险比是普通人的2.42倍,患有带状疱疹后也是一小部分会得癌症,中位在815天后出现。
Results:In total, 2054 cancers were identified in 74 029 patients (13 428 zoster, 60 601 matches). The hazard ratio for cancer diagnosis after zoster was 2.42 (95% confidence interval 2.21, 2.66) and the median time to cancer diagnosis was 815 days. Hazard ratios varied between cancers, and were highest in younger patients. There were more cancers in patients with zoster than those without for all age groups and both genders. Prior immunosuppression was not associated with change in risk, and diagnosis of zoster before cancer did not affect survival.Conclusion:This study establishes an association between zoster and future diagnosis of cancer having implications for cancer case finding after zoster diagnosis.